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Compliance in Controlled E-cigarette Studies
Author(s) -
Meghan E. Rebuli,
Feifei Liu,
Robert Urman,
Jessica L. BarringtonTrimis,
Sandrah P. Eckel,
Rob McConnell,
Ilona Jaspers
Publication year - 2020
Publication title -
nicotine and tobacco research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.338
H-Index - 113
eISSN - 1469-994X
pISSN - 1462-2203
DOI - 10.1093/ntr/ntaa017
Subject(s) - crossover study , cotinine , medicine , electronic cigarette , nicotine , limiting , patient compliance , protocol (science) , compliance (psychology) , psychology , emergency medicine , social psychology , mechanical engineering , alternative medicine , pathology , engineering , placebo
E-cigarette studies have found that the use of a variety of flavors and customizable devices results in greater use frequency and user satisfaction. However, standardized research e-cigarettes are being developed as closed systems with limited flavor options, potentially limiting user satisfaction. In this study, we explore protocol compliance in an e-cigarette study using a standardized, assigned device with puff time and duration tracking (controlled e-cigarette) and potential limitations that controlled devices and e-liquids can introduce.

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