Open AccessWhy does caloric restriction increase life and healthspan? The ‘clean cupboards’ hypothesis
Author(s) -
John R. Speakman
Publication year - 2020
Publication title -
national science review
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.433
H-Index - 54
eISSN - 2095-5138
pISSN - 2053-714X
DOI - 10.1093/nsr/nwaa078
Subject(s) - caloric theory , psychology , biology , endocrinology
The disposable soma hypothesis explanation of the effects of caloric restriction (CR) on lifespan fails to explain why CR generates negative impacts alongside the positive effects and does not work in all species. I propose here a novel idea called the clean cupboards hypothesis which overcomes these problems.
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