Open AccessP04.62 The oncometabolite R-2-Hydroxyglutarate suppresses the innate immune microenvironment of IDH1-mutated gliomas via aryl hydrocarbon receptor signaling
Author(s) -
M Friedrich,
Lukas Bunse,
Theresa Bunse,
E Green,
Tobias Keßler,
Stefan Pusch,
Khwab Sanghvi,
Rafael Carretero,
Ilona Gutcher,
Andreas von Deimling,
Wolfgang Wick,
Michael Platten
Publication year - 2018
Publication title -
neuro-oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.005
H-Index - 125
eISSN - 1523-5866
pISSN - 1522-8517
DOI - 10.1093/neuonc/noy139.296
Subject(s) - immune system , cancer research , biology , tumor microenvironment , aryl hydrocarbon receptor , microglia , glioma , innate immune system , paracrine signalling , microbiology and biotechnology , transcription factor , receptor , immunology , inflammation , gene , biochemistry
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