Open AccessRisk of benign meningioma after childhood cancer in the DCOG-LATER cohort: contributions of radiation dose, exposed cranial volume, and age
Author(s) -
Judith L. Kok,
Jop C. Teepen,
Flora E. van Leeuwen,
Wim J. E. Tissing,
Sebastian Neggers,
Helena J. H. van der Pal,
Jacqueline J. Loonen,
Dorine Bresters,
Birgitta Versluys,
Marry M. van den HeuvelEibrink,
Eline van Dulmenden Broeder,
Margriet van der Heidenvan der Loo,
Berthe M.P. Aleman,
Laurien Daniëls,
Cornelis J.A. Haasbeek,
Bianca A.W. Hoeben,
Geert O. Janssens,
John H. Maduro,
Foppe Oldenburger,
Caroline van Rij,
Robbert J.H.A. Tersteeg,
Michael Hauptmann,
DCOG-LATER Study Group,
M. van den Berg,
Annette H. Bruggink,
H.N. Caron,
Wil V. Dolsma,
Martha A. Grootenhuis,
Jaap G. den Hartogh,
Nynke Hollema,
Marjolijn C.J. Jongmans,
Monique Jaspers,
Alex V. Postma,
Marc J. van de Vijver,
Leontien C.M. Kremer,
Cécile M. Ronckers
Publication year - 2018
Publication title -
neuro-oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.005
H-Index - 125
eISSN - 1523-5866
pISSN - 1522-8517
DOI - 10.1093/neuonc/noy124
Subject(s) - medicine , meningioma , cohort , cancer , proportional hazards model , hazard ratio , radiation therapy , cohort study , cancer registry , relative risk , surgery , nuclear medicine , urology , confidence interval
Pediatric cranial radiotherapy (CrRT) markedly increases risk of meningiomas. We studied meningioma risk factors with emphasis on independent and joint effects of CrRT dose, exposed cranial volume, exposure age, and chemotherapy.
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