Open AccessIdentification of novel recurrent ETV6-IgH fusions in primary central nervous system lymphoma
Author(s) -
Aurélie Bruno,
Karim Labrèche,
Maïlys Daniau,
Blandine Boisselier,
Guillaume Gauchotte,
Louis Royer-Perron,
Amithys Rahimian,
Frédéric Lemoine,
Pierre de la Grange,
Justine Guégan,
Franck Bielle,
Marc Polivka,
Clovis Adam,
David Meyronet,
Dominique FigarellaBranger,
Chiara Villa,
Fabrice Chrétien,
Sandrine Eimer,
Frédéric Davi,
Audrey Rousseau,
Caroline Houillier,
Carole Soussain,
Karima Mokhtari,
Khê HoangXuan,
Agustí Alentorn
Publication year - 2018
Publication title -
neuro-oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.005
H-Index - 125
eISSN - 1523-5866
pISSN - 1522-8517
DOI - 10.1093/neuonc/noy019
Subject(s) - etv6 , fusion gene , haploinsufficiency , biology , fluorescence in situ hybridization , gene rearrangement , cancer research , gene , chromosomal translocation , genetics , phenotype , chromosome
Primary central nervous system lymphoma (PCNSL) represents a particular entity within non-Hodgkin lymphomas and is associated with poor outcome. The present study addresses the potential clinical relevance of chimeric transcripts in PCNSL discovered by using RNA sequencing (RNA-seq).
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