MiR-301a is activated by the Wnt/β-catenin pathway and promotes glioma cell invasion by suppressing SEPT7 | Zendy

Xiao Yue | Zendy; De-Chen Cao | Zendy; Fengming Lan | Zendy; Qiang PanHammarström | Zendy; Tingyi Xia | Zendy; Huiming Yu | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

MiR-301a is activated by the Wnt/β-catenin pathway and promotes glioma cell invasion by suppressing SEPT7

Author(s) -

Xiao Yue,

De-Chen Cao,

Fengming Lan,

Qiang PanHammarström,

Tingyi Xia,

Huiming Yu

Publication year - 2016

Publication title -

neuro-oncology

Language(s) - English

Resource type - Journals

eISSN - 1523-5866

pISSN - 1522-8517

DOI - 10.1093/neuonc/now044

Subject(s) - wnt signaling pathway , glioma , cancer research , biology , carcinogenesis , catenin , microbiology and biotechnology , microrna , signal transduction , cancer , gene , genetics , biochemistry

miR-301a is frequently dysregulated and specific to human tumors, playing a critical role in tumorigenesis; however, the exact functions and regulatory mechanisms of miR-301a in glioma cells remain largely unknown. Herein, we show that miR-301a activated by the Wnt/β-catenin pathway promoted the invasion of glioma cells by directly targeting SEPT7.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research