Open AccessDecrease of VEGF-A in myeloid cells attenuates glioma progression and prolongs survival in an experimental glioma model
Author(s) -
Nadja Osterberg,
Napoleone Ferrara,
Jean Vacher,
Simone Gaedicke,
Gabriele Niedermann,
Astrid Weyerbrock,
Soroush Doostkam,
HansEckart Schaefer,
Karl H. Plate,
Márcia Regina Machein
Publication year - 2016
Publication title -
neuro-oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.005
H-Index - 125
eISSN - 1523-5866
pISSN - 1522-8517
DOI - 10.1093/neuonc/now005
Subject(s) - glioma , cancer research , vegf receptors , medicine , myeloid cells , myeloid
Glioblastomas are highly vascularized tumors with a prominent infiltration of macrophages/microglia whose role in promoting glioma growth, invasion, and angiogenesis has not been fully elucidated.
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