Open AccessCSF neopterin level as a diagnostic marker in primary central nervous system lymphoma
Author(s) -
Aurélien Viaccoz,
François Ducray,
Yannick Tholance,
Gleicy Keli Barcelos,
Laure Thomas-Maisonneuve,
Hervé Ghesquières,
David Meyronet,
Isabelle Quadrio,
Stéphanie CartalatCarel,
G. Louis-Tisserand,
Emmanuel Jouanneau,
Jacques Guyotat,
Jérôme Honnorat,
Armand PerretLiaudet
Publication year - 2015
Publication title -
neuro-oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.005
H-Index - 125
eISSN - 1523-5866
pISSN - 1522-8517
DOI - 10.1093/neuonc/nov092
Subject(s) - neopterin , medicine , differential diagnosis , primary central nervous system lymphoma , brain biopsy , central nervous system , lymphoma , pathology , cerebrospinal fluid , brain tumor , prospective cohort study , lesion , gastroenterology , radiology
The diagnosis of primary central nervous system lymphoma (PCNSL) can be challenging. PCNSL lesions are frequently located deep within the brain, and performing a cerebral biopsy is not always feasible. The aim of this study was to investigate the diagnostic value of CSF neopterin, a marker of neuroinflammation, in immunocompetent patients with suspected PCNSL.
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