Open AccessInvestigation of the diffusion abnormality index as a new imaging biomarker for early assessment of brain tumor response to radiation therapy
Author(s) -
Reza Farjam,
Christina Tsien,
Felix Y. Feng,
Diana GomezHassan,
James A. Hayman,
Theodore S. Lawrence,
Yue Cao
Publication year - 2013
Publication title -
neuro-oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.005
H-Index - 125
eISSN - 1523-5866
pISSN - 1522-8517
DOI - 10.1093/neuonc/not153
Subject(s) - abnormality , diffusion mri , biomarker , brain tumor , diffusion imaging , medicine , imaging biomarker , radiation therapy , psychology , pathology , radiology , magnetic resonance imaging , psychiatry , biology , biochemistry
Diffusion MRI, although having the potential to be a biomarker for early assessment of tumor response to therapy, could be confounded by edema and necrosis in or near the brain tumors. This study aimed to develop and investigate the ability of the diffusion abnormality index (DAI) to be a new imaging biomarker for early assessment of brain metastasis response to radiation therapy (RT).
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