Open AccessThe immune cell infiltrate populating meningiomas is composed of mature, antigen-experienced T and B cells
Author(s) -
Liangjuan Fang,
Daniel E. Lowther,
Matthew L. Meizlish,
Richard C. E. Anderson,
Jeffrey N. Bruce,
Lesley Devine,
Anita Hüttner,
Steven H. Kleinstein,
Ji Yoon Lee,
Joel N. H. Stern,
Gur Yaari,
Laura Lovato,
Katherine M. Cronk,
Kevin C. O’Connor
Publication year - 2013
Publication title -
neuro-oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.005
H-Index - 125
eISSN - 1523-5866
pISSN - 1522-8517
DOI - 10.1093/neuonc/not110
Subject(s) - immune system , antigen , biology , immunology
Meningiomas often harbor an immune cell infiltrate that can include substantial numbers of T and B cells. However, their phenotype and characteristics remain undefined. To gain a deeper understanding of the T and B cell repertoire in this tumor, we characterized the immune infiltrate of 28 resected meningiomas representing all grades.
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