Open AccessMalignant astrocytomas of elderly patients lack favorable molecular markers: an analysis of the NOA-08 study collective
Author(s) -
Benedikt Wiestler,
Rainer Claus,
Sabine Hartlieb,
Maximilian G. Schliesser,
Elisa K. Weiß,
Thomas Hielscher,
Michael Platten,
L M Dittmann,
Christoph Meisner,
Jörg Felsberg,
Caroline Happold,
Matthias Simon,
Guido Nikkhah,
Kirsten Papsdorf,
Jörg Steinbach,
Michael Sabel,
Christian Grimm,
Dieter Weichenhan,
Björn Tews,
Guido Reifenberger,
David Capper,
Wolfram Müller,
Christoph Plass,
Michael Weller,
Wolfgang Wick
Publication year - 2013
Publication title -
neuro-oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.005
H-Index - 125
eISSN - 1523-5866
pISSN - 1522-8517
DOI - 10.1093/neuonc/not043
Subject(s) - medicine
The number of patients age >65 years with malignant gliomas is increasing. Prognosis of these patients is worse compared with younger patients. To determine biological differences among malignant gliomas of different age groups and help to explain the survival heterogeneity seen in the NOA-08 trial, the prevalence and impact of recently established biomarkers for outcome in younger patients were characterized in elderly patients.
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