Open Access1p/19q codeletion and IDH1/2 mutation identified a subtype of anaplastic oligoastrocytomas with prognosis as favorable as anaplastic oligodendrogliomas
Author(s) -
Haihui Jiang,
Xiaohui Ren,
Xiangli Cui,
Junmei Wang,
Wenqing Jia,
Zhiming Zhou,
Song Lin
Publication year - 2013
Publication title -
neuro-oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.005
H-Index - 125
eISSN - 1523-5866
pISSN - 1522-8517
DOI - 10.1093/neuonc/not027
Subject(s) - medicine , idh1 , anaplastic astrocytoma , oncology , oligodendroglial tumor , oligodendroglioma , progression free survival , proportional hazards model , survival analysis , astrocytoma , biomarker , overall survival , gastroenterology , pathology , glioma , mutation , cancer research , biology , gene , genetics
Anaplastic astrocytoma (AA), anaplastic oligoastrocytoma (AOA), and anaplastic oligodendroglioma (AO) are the major histological subtypes of World Health Organization grade III gliomas. More evidence suggests that AOA is unlikely to be a distinct entity, and re-evaluation of this issue has been recommended. In this study, we divided AOA into 2 subgroups, according to molecular biomarkers, and compared the survivals between them.
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