Identifying dysfunctional miRNA-mRNA regulatory modules by inverse activation, cofunction, and high interconnection of target genes: A case study of glioblastoma | Zendy

Yun Xiao | Zendy; Yanyan Ping | Zendy; Huihui Fan | Zendy; Chun Xu | Zendy; Jian Guan | Zendy; Hui Zhao | Zendy; Yihong Li | Zendy; Yuan Lv | Zendy; Yinji Jin | Zendy; Liang Wang | Zendy; Xin Li | Zendy

Open Access

Identifying dysfunctional miRNA-mRNA regulatory modules by inverse activation, cofunction, and high interconnection of target genes: A case study of glioblastoma

Author(s) -

Yun Xiao,

Yanyan Ping,

Huihui Fan,

Chun Xu,

Jian Guan,

Hui Zhao,

Yihong Li,

Yuan Lv,

Yinji Jin,

Liang Wang,

Xin Li

Publication year - 2013

Publication title -

neuro-oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.005

H-Index - 125

eISSN - 1523-5866

pISSN - 1522-8517

DOI - 10.1093/neuonc/not018

Subject(s) - microrna , biology , dysfunctional family , gene , function (biology) , computational biology , messenger rna , genetics , bioinformatics , medicine , clinical psychology

Accumulating evidence demonstrates that complex diseases may arise from cooperative effects of multiple dysfunctional miRNAs. Thus, identifying abnormal functions cooperatively regulated by multiple miRNAs is useful for understanding the pathogenesis of complex diseases.

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