Evaluation of children with craniopharyngioma using carbon-11 methionine PET prior to proton therapy
Author(s) -
B. Laser,
Thomas E. Merchant,
Daniel J. Indelicato,
ChiaHo Hua,
Barry L. Shulkin,
Scott E. Snyder
Publication year - 2013
Publication title -
neuro-oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.005
H-Index - 125
eISSN - 1523-5866
pISSN - 1522-8517
DOI - 10.1093/neuonc/nos321
Subject(s) - craniopharyngioma , medicine , standardized uptake value , nuclear medicine , positron emission tomography , white matter , brain tumor , magnetic resonance imaging , radiology , pathology
Fluorine-18 ((18)F) fluorodeoxyglucose (FDG) positron emission tomography (PET) is limited in its evaluation of brain tumors due to the high basal activity of the cerebral cortex and white matter. Carbon-11 methionine ((11)C MET) has little uptake under normal conditions. We prospectively investigated the uptake of (18)F FDG and (11)C MET PET in patients with craniopharyngioma prior to proton therapy.
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