Open AccessNanoparticles for treating brain tumors: unlimited possibilities
Author(s) -
C. David James
Publication year - 2012
Publication title -
neuro-oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.005
H-Index - 125
eISSN - 1523-5866
pISSN - 1522-8517
DOI - 10.1093/neuonc/nos075
Subject(s) - nanoparticle , distribution (mathematics) , in vivo , brain tumor , cancer therapy , nanotechnology , medicine , cancer , materials science , pathology , mathematics , biology , mathematical analysis , microbiology and biotechnology
The use of nanoparticles to improve the distribution and extend the duration of exposure to therapy continues to be investigated and applied in cancer research and treatment, respectively, more than 30 years subsequent to the earliest publications involving its use in experimental tumor models in vivo. Nanoparticle packaging of therapy is of particular interest for its potential to treat brain tumors because of the favorable CNS distribution of many nanoparticle drug formulations.
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