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Long-term expression of glomerular genes in diabetic nephropathy
Author(s) -
Dominik Chittka,
Bernhard Banas,
L. Lennartz,
Franz Josef Putz,
Kathrin Eidenschink,
Sebastian Beck,
Thomas Stempfl,
Christoph Moehle,
Simone ReicheltWurm,
Miriam C. Banas
Publication year - 2017
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfx359
Subject(s) - diabetic nephropathy , endocrinology , medicine , diabetes mellitus , kidney , renal cortex , downregulation and upregulation , type 2 diabetes , nephropathy , gene , biology , genetics
Although diabetic nephropathy (DN) is the most common cause for end-stage renal disease in western societies, its pathogenesis still remains largely unclear. A different gene pattern of diabetic and healthy kidney cells is one of the probable explanations. Numerous signalling pathways have emerged as important pathophysiological mechanisms for diabetes-induced renal injury.

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