Open AccessUrinary mitochondrial DNA level is an indicator of intra-renal mitochondrial depletion and renal scarring in diabetic nephropathy
Author(s) -
Pascal Zhongping Wei,
Bonnie ChingHa Kwan,
Kai Ming Chow,
Phyllis MeiShan Cheng,
Cathy ChoiWan Luk,
Philip KamTao Li,
CheukChun Szeto
Publication year - 2017
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfx339
Subject(s) - urinary system , renal function , medicine , kidney , diabetic nephropathy , urology , mitochondrial dna , nephropathy , urine , renal biopsy , diabetes mellitus , endocrinology , biology , biochemistry , gene
Mitochondrial dysfunction plays an important role in the pathogenesis and progression of diabetic nephropathy (DN). We study the relation between urinary and intra-renal mitochondrial deoxyribonucleic acid (mtDNA) levels and renal dysfunction in DN.
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