Kidney injury molecule-1 staining in renal allograft biopsies 10 days after transplantation is inversely correlated with functioning proximal tubular epithelial cells | Zendy

Jonna R. Bank | Zendy; Pieter van der Pol | Zendy; Dianne Vreeken | Zendy; Catherine Monge-Chaubo | Zendy; Ingeborg M. Bajema | Zendy; Nicole Schlagwein | Zendy; D.J. van Gijlswijk | Zendy; Sandra W. van der Kooij | Zendy; Marlies E. J. Reinders | Zendy; Johan W. de Fijter | Zendy; Cees van Kooten | Zendy

Open Access

Kidney injury molecule-1 staining in renal allograft biopsies 10 days after transplantation is inversely correlated with functioning proximal tubular epithelial cells

Author(s) -

Jonna R. Bank,

Pieter van der Pol,

Dianne Vreeken,

Catherine Monge-Chaubo,

Ingeborg M. Bajema,

Nicole Schlagwein,

D.J. van Gijlswijk,

Sandra W. van der Kooij,

Marlies E. J. Reinders,

Johan W. de Fijter,

Cees van Kooten

Publication year - 2017

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfx286

Subject(s) - medicine , lipocalin , transplantation , staining , acute tubular necrosis , kidney , pathology , kidney transplantation , urinary system , renal function , urology

Kidney injury molecule-1 (KIM-1) and neutrophil gelatinase-associated lipocalin (NGAL) are promising biomarkers for monitoring delayed graft function (DGF) after kidney transplantation. Here we investigated localization and distribution of KIM-1 and NGAL staining in renal allograft biopsies and studied their association with histological features, functional DGF (fDGF) and the tubular function slope (TFS), a functioning proximal tubular epithelial cell (PTEC) marker.

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