Hereditary polycystic kidney disease is characterized by lymphopenia across all stages of kidney dysfunction: an observational study | Zendy

Steven Van Laecke | Zendy; Tessa Kerre | Zendy; Evi Nagler | Zendy; Bart Maes | Zendy; Rogier Caluwé | Zendy; Eva Schepers | Zendy; Griet Glorieux | Zendy; Wim Van Biesen | Zendy; Francis Verbeke | Zendy

Open Access

Hereditary polycystic kidney disease is characterized by lymphopenia across all stages of kidney dysfunction: an observational study

Author(s) -

Steven Van Laecke,

Tessa Kerre,

Evi Nagler,

Bart Maes,

Rogier Caluwé,

Eva Schepers,

Griet Glorieux,

Wim Van Biesen,

Francis Verbeke

Publication year - 2017

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfx040

Subject(s) - medicine , kidney disease , polycystic kidney disease , cohort , nephrology , autosomal dominant polycystic kidney disease , kidney transplantation , renal function , kidney , gastroenterology , endocrinology

Polycystic kidney disease (PKD) is characterized by urinary tract infections and extrarenal abnormalities such as an increased risk of cancer. As mutations in polycystin-1 and -2 are associated with decreased proliferation of immortalized lymphoblastoid cells in PKD, we investigated whether lymphopenia could be an unrecognized trait of PKD.

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