Open AccessMagnesium lactate in the treatment of Gitelman syndrome: patient-reported outcomes
Author(s) -
Caroline Robinson,
Fiona E. Karet
Publication year - 2016
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfw019
Subject(s) - medicine , tubulopathy , gitelman syndrome , hypomagnesemia , hypokalemia , gastroenterology , magnesium , endocrinology , kidney , materials science , metallurgy
Gitelman syndrome (GS) is a rare recessively inherited renal tubulopathy associated with renal potassium (K) and magnesium (Mg) loss. It requires lifelong K and Mg supplementation at high doses that are at best unpalatable and at worst, intolerable. In particular, gastrointestinal side effects often limit full therapeutic usage.
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