Peritoneal inflammation precedes encapsulating peritoneal sclerosis: results from the GLOBAL Fluid Study | Zendy

Mark Lambie | Zendy; James Chess | Zendy; Angela Summers | Zendy; Paul F. Williams | Zendy; Nicholas Topley | Zendy; Simon Davies | Zendy

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Peritoneal inflammation precedes encapsulating peritoneal sclerosis: results from the GLOBAL Fluid Study

Author(s) -

Mark Lambie,

James Chess,

Angela Summers,

Paul F. Williams,

Nicholas Topley,

Simon Davies

Publication year - 2016

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfv440

Subject(s) - medicine , peritoneal dialysis , peritoneal fluid , peritoneal cavity , fibrosis , gastroenterology , inflammation , peritoneum , peritonitis , tumor necrosis factor alpha , confidence interval , immunology , surgery

Encapsulating peritoneal sclerosis (EPS) is an uncommon condition, strongly associated with a long duration of peritoneal dialysis (PD), which is itself associated with increased fibrosis in the peritoneal membrane. The peritoneal membrane is inflamed during PD and inflammation is often associated with fibrosis. We hypothesized that patients who subsequently develop EPS might have a more inflamed peritoneal membrane during PD.

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