Individual long-term albuminuria exposure during angiotensin receptor blocker therapy is the optimal predictor for renal outcome
Author(s) -
Tobias F. Kröpelin,
Dick de Zeeuw,
Frank A. Holtkamp,
David Packham,
Hiddo J.L. Heerspink
Publication year - 2016
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfv429
Subject(s) - albuminuria , medicine , urology , receiver operating characteristic , endocrinology , kidney disease
Albuminuria reduction due to angiotensin receptor blockers (ARBs) predicts subsequent renoprotection. Relating the initial albuminuria reduction to subsequent renoprotection assumes that the initial ARB-induced albuminuria reduction remains stable during follow-up. The aim of this study was to assess individual albuminuria fluctuations after the initial ARB response and to determine whether taking individual albuminuria fluctuations into account improves renal outcome prediction.
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