Open AccessUrsolic acid improves podocyte injury caused by high glucose
Author(s) -
Xu Li,
Qiuling Fan,
Xu Wang,
Lin Li,
Xinxing Lu,
Yuan Yue,
Xu Cao,
Jia Liu,
Xue Zhao,
Lining Wang
Publication year - 2015
Publication title -
nephrology dialysis transplantation
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfv382
Subject(s) - medicine , podocyte , ursolic acid , endocrinology , kidney , botany , proteinuria , biology
Autophagy plays an important role in the maintenance of podocyte homeostasis. Reduced autophagy may result in limited renal cell function during exposure to high glucose conditions. In this study we investigated the effects of ursolic acid (UA) on autophagy and podocyte injury, which were induced by high glucose.
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