Open AccessEffect of renal impairment on atherosclerosis: only partially mediated by homocysteine
Author(s) -
J. David Spence,
Bradley L. Urquhart,
Heejung Bang
Publication year - 2015
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfv380
Subject(s) - medicine , homocysteine , renal function , cardiology , hyperhomocysteinemia , kidney disease , risk factor , urology
Cardiovascular risk and plasma total homocysteine (tHcy) are high in patients with renal failure. High tHcy may account for a substantial part of the increased risk. We assessed mediation by tHcy of the association of estimated glomerular filtration rate (eGFR CKD/EPI) with carotid total plaque area (TPA) and carotid stenosis.
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