Long-term CD4 lymphopenia is associated with accelerated decline of kidney allograft function | Zendy

Yosu Luque | Zendy; Matthieu Jamme | Zendy; Marion Rabant | Zendy; Susan DeWolf | Zendy; LaureHélène Noël | Zendy; Éric Thervet | Zendy; Lucienne Chatenoud | Zendy; Renaud Snanoudj | Zendy; Dany Anglicheau | Zendy; Christophe Legendre | Zendy; Sophie Candon | Zendy; Julien Zuber | Zendy

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Long-term CD4 lymphopenia is associated with accelerated decline of kidney allograft function

Author(s) -

Yosu Luque,

Matthieu Jamme,

Marion Rabant,

Susan DeWolf,

LaureHélène Noël,

Éric Thervet,

Lucienne Chatenoud,

Renaud Snanoudj,

Dany Anglicheau,

Christophe Legendre,

Sophie Candon,

Julien Zuber

Publication year - 2015

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfv362

Subject(s) - medicine , immunosuppression , dialysis , kidney transplantation , transplantation , kidney , gastroenterology , renal function , cohort , immunology

Persistent CD4 T-cell lymphopenia after kidney transplantation has been associated with an increased occurrence of opportunistic infections, malignancies and even mortality, but studies have focussed only on the first few years after kidney transplantation. In this study, we investigated the risk factors and clinical significance of long-term profound CD4 lymphopenia detected ≥10 years after renal transplantation.

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