Reduced skeletal muscle function is associated with decreased fiber cross-sectional area in the Cy/+ rat model of progressive kidney disease | Zendy

Jason M. Organ | Zendy; Andrew Srisuwananukorn | Zendy; Paige Price | Zendy; J. Ethan Joll | Zendy; Kelly C. Biro | Zendy; Joseph E. Rupert | Zendy; Neal X. Chen | Zendy; Keith G. Avin | Zendy; Sharon M. Moe | Zendy; Matthew R. Allen | Zendy

Open Access

Reduced skeletal muscle function is associated with decreased fiber cross-sectional area in the Cy/+ rat model of progressive kidney disease

Author(s) -

Jason M. Organ,

Andrew Srisuwananukorn,

Paige Price,

J. Ethan Joll,

Kelly C. Biro,

Joseph E. Rupert,

Neal X. Chen,

Keith G. Avin,

Sharon M. Moe,

Matthew R. Allen

Publication year - 2015

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfv352

Subject(s) - medicine , kidney disease , myosin , endocrinology , skeletal muscle , renal function , wasting , in vivo , biology , microbiology and biotechnology , biophysics

The combination of skeletal muscle wasting and compromised function plays a role in the health decline commonly observed in chronic kidney disease (CKD) patients, but the pathophysiology of muscle mass/strength changes remains unclear. The purpose of this study was to characterize muscle properties in the Cy/+ rat model of spontaneously progressive CKD.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research