Open AccessImpact of extracorporeal blood flow rate on blood pressure, pulse rate and cardiac output during haemodialysis
Author(s) -
Philip Andreas Schytz,
Maria L. Mace,
Anne Merete Boas Soja,
Brian Nilsson,
Nikolaos Karamperis,
Bent Bruun Kristensen,
Søren Daustrand Ladefoged,
Henrik Post Hansen
Publication year - 2015
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfv316
Subject(s) - medicine , blood pressure , crossover study , pulse pressure , cardiology , extracorporeal , diastole , hemodialysis , cardiac output , hemodynamics , blood flow , mean arterial pressure , mean blood pressure , anesthesia , heart rate , alternative medicine , pathology , placebo
If blood pressure (BP) falls during haemodialysis (HD) [intradialytic hypotension (IDH)] a common clinical practice is to reduce the extracorporeal blood flow rate (EBFR). Consequently the efficacy of the HD (Kt/V) is reduced. However, only very limited knowledge on the effect of reducing EBFR on BP exists and data are conflicting. The aim of this study was to evaluate the effect and the potential mechanism(s) involved by investigating the impact of changes in EBFR on BP, pulse rate (PR) and cardiac output (CO) in HD patients with arteriovenous-fistulas (AV-fistulas).
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