Early renal graft function deterioration in recipients with preformed anti-MICA antibodies: partial contribution of complement-dependent cytotoxicity | Zendy

Elena SánchezZapardiel | Zendy; María José Castro-Panete | Zendy; Esther Mancebo | Zendy; Pablo Morales | Zendy; Rocío LagunaGoya | Zendy; José María Morales | Zendy; Jacqueline Apaza | Zendy; Amado de Andrés | Zendy; Paloma Talayero | Zendy; Estela PazArtal | Zendy

Open Access

Early renal graft function deterioration in recipients with preformed anti-MICA antibodies: partial contribution of complement-dependent cytotoxicity

Author(s) -

Elena SánchezZapardiel,

María José Castro-Panete,

Esther Mancebo,

Pablo Morales,

Rocío LagunaGoya,

José María Morales,

Jacqueline Apaza,

Amado de Andrés,

Paloma Talayero,

Estela PazArtal

Publication year - 2015

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfv308

Subject(s) - medicine , renal function , mica , antibody , kidney transplantation , transplantation , human leukocyte antigen , creatinine , immunology , complement dependent cytotoxicity , gastroenterology , hazard ratio , urology , antibody dependent cell mediated cytotoxicity , antigen , biology , monoclonal antibody , confidence interval , paleontology

We previously reported that preformed anti-MHC class I-related chain A (MICA) antibodies increase the risk for renal graft rejection and enhance the deleterious effect of PRA(+) status early after transplantation.

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