Histologic versus clinical remission in proliferative lupus nephritis
Author(s) -
Ana Malvar,
Paola Pirruccio,
Valeria Albertón,
Bruno Lococo,
Cecilia Recalde,
Bernanda Fazini,
Haikady N. Nagaraja,
Divya Indrakanti,
Brad H. Rovin
Publication year - 2015
Publication title -
nephrology dialysis transplantation
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfv296
Subject(s) - medicine , lupus nephritis , nephritis , immunology , pathology , gastroenterology , disease
Treatment response in lupus nephritis (LN) is defined clinically, without consideration of renal histology. Few studies have systematically examined histologic responses to induction therapy. In LN patients who underwent protocol kidney biopsies after induction immunosuppression, we describe the renal histology of the second biopsy and correlate histologic activity and damage with short- and long-term kidney outcomes.
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