New insights in molecular mechanisms involved in chronic kidney disease using high-resolution plasma proteome analysis | Zendy

Griet Glorieux | Zendy; William Mullen | Zendy; Flore Duranton | Zendy; Szymon K. Filip | Zendy; Nathalie Gayrard | Zendy; Holger Husi | Zendy; Eva Schepers | Zendy; Nathalie Neirynck | Zendy; Joost P. Schanstra | Zendy; Joachim Jankowski | Zendy; Harald Mischak | Zendy; Àngel Argilés | Zendy; Raymond Vanholder | Zendy; Antonia Vlahou | Zendy; Julie Klein | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

New insights in molecular mechanisms involved in chronic kidney disease using high-resolution plasma proteome analysis

Author(s) -

Griet Glorieux,

William Mullen,

Flore Duranton,

Szymon K. Filip,

Nathalie Gayrard,

Holger Husi,

Eva Schepers,

Nathalie Neirynck,

Joost P. Schanstra,

Joachim Jankowski,

Harald Mischak,

Àngel Argilés,

Raymond Vanholder,

Antonia Vlahou,

Julie Klein

Publication year - 2015

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfv254

Subject(s) - kidney disease , medicine , proteome , renal function , blood proteins , kidney , endocrinology , bioinformatics , biology

The reduced glomerular filtration rate in the advanced stages of chronic kidney disease (CKD) leads to plasma accumulation of uraemic retention solutes including proteins. It has been hypothesized that these changes may, at least in part, be responsible for CKD-associated morbidity and mortality. However, most studies focused on the role of individual proteins, while a holistic, large-scale, integrative approach may generate significant additional insight.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research