Interstitial eosinophilic aggregates in diabetic nephropathy: allergy or not?
Author(s) -
DaoFu Dai,
Kotaro Sasaki,
Mercury Lin,
Kelly D. Smith,
Roberto F. Nicosia,
Charles E. Alpers,
Behzad Najafian
Publication year - 2015
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfv067
Subject(s) - medicine , diabetic nephropathy , eosinophilic , interstitial nephritis , nephropathy , drug allergy , nephritis , allergy , diabetes mellitus , dermatology , pathology , immunology , kidney , endocrinology
Interstitial eosinophilic aggregates (IEA) in renal biopsies often suggest allergic tubulointerstitial nephritis, yet clear associations with drug reactions are often difficult to establish. IEA are also encountered in diabetic nephropathy (DN) and thought to be attributed to medication exposure.
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