Altered monocyte expression and expansion of non-classical monocyte subset in IgA nephropathy patients | Zendy

Sharon Natasha Cox | Zendy; Grazia Serino | Zendy; Fabio Sallustio | Zendy; Antonella Blasi | Zendy; Michele Rossini | Zendy; Francesco Pesce | Zendy; Francesco Paolo Schena | Zendy

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Altered monocyte expression and expansion of non-classical monocyte subset in IgA nephropathy patients

Author(s) -

Sharon Natasha Cox,

Grazia Serino,

Fabio Sallustio,

Antonella Blasi,

Michele Rossini,

Francesco Pesce,

Francesco Paolo Schena

Publication year - 2015

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfv017

Subject(s) - cd14 , monocyte , medicine , peripheral blood mononuclear cell , immunology , cd16 , nephropathy , flow cytometry , immune system , biology , endocrinology , cd8 , diabetes mellitus , biochemistry , cd3 , in vitro

The main defect of immunoglobulin A nephropathy (IgAN) lies within the immune system and in peripheral blood mononuclear cells rather than in the kidney. Previously, we found an altered gene expression in monocytes compared with B and T cells isolated from IgAN patients; thus, our aim here has been to study this subset at a genome-wide and functional level.

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