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Enteric hyperoxaluria: an important cause of end-stage kidney disease
Author(s) -
Lama Nazzal,
Isha Puri,
David S. Goldfarb
Publication year - 2015
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfv005
Subject(s) - medicine , nephrocalcinosis , kidney disease , kidney stones , complication , disease , primary hyperoxaluria , gastroenterology , end stage renal disease , inflammatory bowel disease , kidney
Hyperoxaluria is a frequent complication of inflammatory bowel diseases, ileal resection and Roux-en-Y gastric bypass and is well-known to cause nephrolithiasis and nephrocalcinosis. The associated prevalence of chronic kidney disease and end-stage kidney disease (ESKD) is less clear but may be more consequential than recognized. In this review, we highlight three cases of ESKD due to enteric hyperoxaluria following small bowel resections. We review current information on the pathophysiology, complications and treatment of this complex disease.

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