Pro-inflammatory cytokines and leukocyte oxidative burst in chronic kidney disease: culprits or innocent bystanders? | Zendy

Nathalie Neirynck | Zendy; Griet Glorieux | Zendy; Eva Schepers | Zendy; Annemieke Dhondt | Zendy; Francis Verbeke | Zendy; Raymond Vanholder | Zendy

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Pro-inflammatory cytokines and leukocyte oxidative burst in chronic kidney disease: culprits or innocent bystanders?

Author(s) -

Nathalie Neirynck,

Griet Glorieux,

Eva Schepers,

Annemieke Dhondt,

Francis Verbeke,

Raymond Vanholder

Publication year - 2015

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfu409

Subject(s) - medicine , oxidative stress , inflammation , immunology , kidney disease , inflammatory response , proinflammatory cytokine , disease , respiratory burst , kidney , cytokine

Pro-inflammatory cytokines are elevated in chronic kidney disease (CKD), a condition characterized by microinflammation with oxidative stress as key feature. However, their role in the inflammatory response at uraemic concentrations has not yet been defined. In this study, the contribution of cytokines on induction of leukocyte oxidative stress was investigated.

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