Impact of westernization on fibroblast growth factor 23 levels among individuals of African ancestry | Zendy

Kara Eckberg | Zendy; Holly Kramer | Zendy; Michael S. Wolf | Zendy; Ramón Durazo-Arvizú | Zendy; Bamidele O. Tayo | Zendy; Amy Luke | Zendy; Richard Cooper | Zendy

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Impact of westernization on fibroblast growth factor 23 levels among individuals of African ancestry

Author(s) -

Kara Eckberg,

Holly Kramer,

Michael S. Wolf,

Ramón Durazo-Arvizú,

Bamidele O. Tayo,

Amy Luke,

Richard Cooper

Publication year - 2014

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfu342

Subject(s) - medicine , fibroblast growth factor 23 , urine , interquartile range , body mass index , creatinine , excretion , gerontology , demography , physiology , parathyroid hormone , sociology , calcium

The Western diet is associated with high consumption of processed foods preserved with phosphate. Higher dietary phosphate consumption stimulates production of fibroblast growth factor 23 (FGF23), which heightens risk for cardiovascular disease and mortality. We hypothesized that adults living in a more westernized society have higher levels of FGF23 due to increased phosphate consumption as measured by urinary phosphate excretion.

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