Omega-3 fatty acids inhibit the up-regulation of endothelial chemokines in maintenance hemodialysis patients | Zendy

Adriana M. Hung | Zendy; Catriona Booker | Zendy; Charles D. Ellis | Zendy; Edward D. Siew | Zendy; Amy J. Graves | Zendy; Ayumi Shintani | Zendy; Naji N. Abumrad | Zendy; Jonathan Himmelfarb | Zendy; T. Alp İkizler | Zendy

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Omega-3 fatty acids inhibit the up-regulation of endothelial chemokines in maintenance hemodialysis patients

Author(s) -

Adriana M. Hung,

Catriona Booker,

Charles D. Ellis,

Edward D. Siew,

Amy J. Graves,

Ayumi Shintani,

Naji N. Abumrad,

Jonathan Himmelfarb,

T. Alp İkizler

Publication year - 2014

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfu283

Subject(s) - medicine , docosahexaenoic acid , eicosapentaenoic acid , hemodialysis , interquartile range , immunology , systemic inflammation , kidney disease , gastroenterology , population , polyunsaturated fatty acid , peripheral blood mononuclear cell , placebo , dialysis , inflammation , endocrinology , fatty acid , pathology , biochemistry , chemistry , environmental health , organic chemistry , in vitro , alternative medicine

Chronic systemic inflammation is common in patients with chronic kidney disease on dialysis (CKD5D) and has been considered a key mediator of the increased cardiovascular risk in this patient population. In this study, we tested the hypothesis that supplementation of omega-3 polyunsaturated fatty acids (ω-3 PUFAs) will attenuate the systemic inflammatory process in CKD5D patients.

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