Vagal stimulation in brain dead donor rats decreases chronic allograft nephropathy in recipients
Author(s) -
Simone Hoeger,
J. Fontana,
Jonas Jarczyk,
Jochen Selhorst,
R. Waldherr,
Bernhard K. Krämer,
Peter Schnuelle,
Benito A. Yard
Publication year - 2013
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gft451
Subject(s) - medicine , vagus nerve stimulation , vagus nerve , chronic allograft nephropathy , stimulation , transplantation , renal function , urology , nephropathy , kidney transplantation , gastroenterology , endocrinology , diabetes mellitus
Although it has been shown that a vagus nerve stimulation of brain dead (BD) donors leads to an improvement of renal function in recipients in an acute allograft rejection model, its influence on chronic allograft nephropathy is still unknown. In the present study, we assessed the influence of donor vagus nerve stimulation on survival, renal function and histology in a chronic allograft model.
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