Open AccessObesity and CKD progression: hard facts on fat CKD patients
Author(s) -
Francesca Mallamaci,
Giovanni Tripepi
Publication year - 2013
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gft391
Subject(s) - medicine , kidney disease , obesity , pathogenesis , kidney , disease , intensive care medicine , endocrinology , bioinformatics , biology
Obesity is a worldwide epidemic and there is compelling evidence that excess fat is closely associated with chronic kidney disease (CKD) and end-stage kidney failure. In this review, we will describe some important mechanisms related with the pathogenesis and treatment of CKD in obesity by emphasizing the role of excess fat in renal haemodynamic and structural alterations.
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