Effects of uric acid-lowering therapy on renal outcomes: a systematic review and meta-analysis
Author(s) -
Bhadran Bose,
Sunil V. Badve,
Swapnil Hiremath,
Neil Boudville,
Fiona G. Brown,
Alan Cass,
Janak de Zoysa,
Robert G. Fassett,
Randall Faull,
David C.H. Harris,
Carmel M. Hawley,
John Kanellis,
Suetonia C. Palmer,
Vlado Perkovic,
Elaine M. Pascoe,
Gopala K. Rangan,
Robert Walker,
Giles Walters,
David W. Johnson
Publication year - 2013
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gft378
Subject(s) - medicine , meta analysis , uric acid , intensive care medicine , systematic review , medline , urology , biochemistry , chemistry
Non-randomized studies suggest an association between serum uric acid levels and progression of chronic kidney disease (CKD). The aim of this systematic review is to summarize evidence from randomized controlled trials (RCTs) concerning the benefits and risks of uric acid-lowering therapy on renal outcomes.
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