The impact of dietary magnesium restriction on magnesiotropic and calciotropic genes
Author(s) -
Annelies A. van Angelen,
Pedro SanCristobal,
W. P. Pulskens,
Joost G.J. Hoenderop,
René J.M. Bindels
Publication year - 2013
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gft358
Subject(s) - medicine , endocrinology , distal convoluted tubule , kidney , excretion , reabsorption
Magnesium (Mg(2+)) is an essential electrolyte with important physiological functions. Consequently, hypomagnesaemia, an electrolyte disorder frequently diagnosed in critically ill patients, can have life-threatening consequences. The kidney plays a central role in the regulation of the Mg(2+) balance. The present study investigated the molecular consequences of dietary Mg(2+) restriction on renal Mg(2+) transporters.
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