Postprandial responses of incretin and pancreatic hormones in non-diabetic patients with end-stage renal disease | Zendy

Thomas Idorn | Zendy; Filip K. Knop | Zendy; Morten Buus Jørgensen | Zendy; Jens J. Holst | Zendy; Mads Hornum | Zendy; Bo FeldtRasmussen | Zendy

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Postprandial responses of incretin and pancreatic hormones in non-diabetic patients with end-stage renal disease

Author(s) -

Thomas Idorn,

Filip K. Knop,

Morten Buus Jørgensen,

Jens J. Holst,

Mads Hornum,

Bo FeldtRasmussen

Publication year - 2013

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gft353

Subject(s) - postprandial , medicine , incretin , endocrinology , gastric inhibitory polypeptide , gastric emptying , glucagon , glucagon like peptide 1 , hormone , prediabetes , insulin , diabetes mellitus , type 2 diabetes , stomach

Patients with end-stage renal disease (ESRD) have glucometabolic disturbances resulting in a high prevalence of prediabetes. The underlying pathophysiology remains unclear, but may prove important for the strategies employed to prevent progression to overt diabetes. Meal-induced release of the insulinotropic gut-derived incretin hormones and pancreatic hormones play a critical role in the maintenance of a normal postprandial glucose tolerance.

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