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Renal vein cytokine release as an index of renal parenchymal inflammation in chronic experimental renal artery stenosis
Author(s) -
Alfonso Eirin,
Xin Zhang,
Xiang-Yang Zhu,
Hui Tang,
Kyra L. Jordan,
Joseph P. Grande,
Allan B. Dietz,
Amir Lerman,
Stephen C. Textor,
Lilach O. Lerman
Publication year - 2013
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gft305
Subject(s) - medicine , inflammation , kidney , parenchyma , renal artery stenosis , cytokine , stenosis , renal vein , renal artery , pathology , kidney disease , vein , nephrology
Renal parenchymal inflammation is a critical determinant of kidney injury in renal artery stenosis (RAS) but is difficult to assess in the single kidney without tissue samples. Whether renal vein (RV) levels of inflammatory markers reflect active parenchymal inflammation remains unknown. We evaluated the relationship between net RV cytokine release and tissue inflammation in the post-stenotic kidney.

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