Fondaparinux as an alternative to vitamin K antagonists in haemodialysis patients
Author(s) -
Marijn M. Speeckaert,
Katrien Devreese,
Raymond Vanholder,
Annemieke Dhondt
Publication year - 2013
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gft293
Subject(s) - medicine , fondaparinux , calciphylaxis , dialysis , anticoagulant , hemodialysis , heparin , vitamin k , vitamin d and neurology , coumarin , intensive care medicine , calcification , venous thromboembolism , thrombosis , botany , biology
Accelerated vascular calcification and increased risk of calciphylaxis can be a reason to restrict the use of vitamin K antagonists in dialysis patients. We describe the use of fondaparinux, a prototype indirect factor Xa inhibitor, as an alternative anticoagulant to coumarin derivatives in dialysis patients.
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