A single-blind randomized controlled trial to evaluate the effect of 6 months of progressive aerobic exercise training in patients with uraemic restless legs syndrome | Zendy

Christoforos D. Giannaki | Zendy; Georgios M. Hadjigeorgiou | Zendy; Christina Karatzaferi | Zendy; Μaria Maridaki | Zendy; Yiannis Koutedakis | Zendy; Paraskevi Founta | Zendy; Nikolaos Tsianas | Zendy; Ioannis Stefanidis | Zendy; Giorgos K. Sakkas | Zendy

Open Access

A single-blind randomized controlled trial to evaluate the effect of 6 months of progressive aerobic exercise training in patients with uraemic restless legs syndrome

Author(s) -

Christoforos D. Giannaki,

Georgios M. Hadjigeorgiou,

Christina Karatzaferi,

Μaria Maridaki,

Yiannis Koutedakis,

Paraskevi Founta,

Nikolaos Tsianas,

Ioannis Stefanidis,

Giorgos K. Sakkas

Publication year - 2013

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gft288

Subject(s) - medicine , randomized controlled trial , physical therapy , restless legs syndrome , physical exercise , aerobic exercise , adverse effect , insomnia , psychiatry

Uraemic restless legs syndrome (RLS) affects a significant proportion of patients receiving haemodialysis (HD) therapy. Exercise training has been shown to improve RLS symptoms in uraemic RLS patients; however, the mechanism of exercise-induced changes in RLS severity is still unknown. The aim of the current randomized controlled exercise trial was to investigate whether the reduction of RLS severity, often seen after training, is due to expected systemic exercise adaptations or it is mainly due to the relief that leg movements confer during exercise training on a cycle ergometer. This is the first randomized controlled exercise study in uraemic RLS patients.

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