Vitamin D receptor activation, left ventricular hypertrophy and myocardial fibrosis
Author(s) -
Sara Panizo,
S. Barrio-Vazquez,
Manuel NavesDíaz,
Natalia CarrilloLópez,
Isabel Rodrı́guez,
Amalia Fernández-Vázquez,
José Manuel Valdivielso,
Ravi Thadhani,
Jorge B. CannataAndía
Publication year - 2013
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gft268
Subject(s) - medicine , paricalcitol , endocrinology , left ventricular hypertrophy , fibrosis , myocardial fibrosis , calcitriol receptor , brain natriuretic peptide , cardiac fibrosis , atrial natriuretic peptide , kidney disease , calcitriol , natriuretic peptide , ventricular remodeling , vitamin d and neurology , heart failure , blood pressure , calcium , secondary hyperparathyroidism , parathyroid hormone
Left ventricular hypertrophy (LVH), a common complication in chronic kidney disease (CKD), is associated with high cardiovascular mortality. The aim of this experimental study was to analyze the effect of different vitamin D receptor activators (VDRAs) on both LVH and myocardial fibrosis in chronic renal failure (CRF).
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