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Renal transplantation normalizes baroreflex sensitivity through improvement in central arterial stiffness
Author(s) -
Manpreet Kaur,
D Suba Chandran,
Chitra Lal,
Dipankar Bhowmik,
Ashok Kumar Jaryal,
K. K. Deepak,
Surendra Kumar Agarwal
Publication year - 2013
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gft099
Subject(s) - medicine , arterial stiffness , baroreflex , cardiology , blood pressure , pulse wave velocity , pulse pressure , transplantation , kidney disease , end stage renal disease , heart rate variability , heart rate , hemodialysis
In end-stage renal disease (ESRD) patients, the most common cause of mortality and morbidity are cardiovascular events. This could be attributed to the impaired baroreflex function observed in this group of patients. The effect of renal transplantation (RT) on the baroreflex sensitivity (BRS) in ESRD patients has been inadequately addressed. Therefore, we investigated baroreflex function and its relation to arterial stiffness indices and cardiovascular variability parameters (heart rate and blood pressure variability--HRV and BPV) in ESRD patients before and after transplantation to decipher the underlying mechanism of attenuated BRS in ESRD patients.

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