Open AccessPost-ischemic azotemia as a partial ‘brake’, slowing progressive kidney disease
Author(s) -
Richard A. Zager,
Ali C.M. Johnson,
K Becker
Publication year - 2013
Publication title -
nephrology dialysis transplantation
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gft040
Subject(s) - medicine , azotemia , kidney disease , cardiology , renal function
Recent experimental work suggests a paradox: although uremia evokes systemic toxicities, in the setting of AKI, it can induce intrarenal cytoprotective and anti-inflammatory effects. Whether these influences can attenuate post-ischemic kidney disease progression remains unknown.
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