Open AccessSurvival and distribution of injected haematopoietic stem cells in acute kidney injury
Author(s) -
Volker Burst,
Florian Pütsch,
Torsten Kubacki,
Linus A. Völker,
Malte P. Bartram,
RomanUlrich Müller,
Meyke Gillis,
Christine Kurschat,
Franziska Grundmann,
Jochen MüllerEhmsen,
Thomas Benzing,
Sven Teschner
Publication year - 2012
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfs513
Subject(s) - haematopoiesis , renal stem cell , medicine , stem cell , mesenchymal stem cell , acute kidney injury , kidney , bone marrow , pathology , cancer research , microbiology and biotechnology , biology , progenitor cell
Endogenous bone marrow-derived cells are known to incorporate into renal epithelium at a low rate. Haematopoietic stem cells (HSCs) rather than mesenchymal stem cells (MSC) are responsible for this phenomenon. MSCs have the potential to ameliorate kidney function after acute kidney injury (AKI) without directly repopulating the tubules. However, little is known about the short-term effect of HSCs.
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