Serum uric acid, kidney volume and progression in autosomal-dominant polycystic kidney disease | Zendy

Imed Helal | Zendy; Kim McFann | Zendy; Berenice Reed | Zendy; Xiang-Dong Yan | Zendy; Robert W. Schrier | Zendy; Godela M. Fick-Brosnahan | Zendy

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Serum uric acid, kidney volume and progression in autosomal-dominant polycystic kidney disease

Author(s) -

Imed Helal,

Kim McFann,

Berenice Reed,

Xiang-Dong Yan,

Robert W. Schrier,

Godela M. Fick-Brosnahan

Publication year - 2012

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfs417

Subject(s) - medicine , autosomal dominant polycystic kidney disease , uric acid , polycystic kidney disease , kidney disease , kidney , disease , endocrinology , risk factor , pathology

Hyperuricemia has been implicated in the development and progression of chronic kidney disease, both in animal experiments and in clinical studies. As a potentially modifiable risk factor, we examined whether serum uric acid levels correlate with early hypertension, kidney volume and progression to end-stage renal disease (ESRD) in autosomal-dominant polycystic kidney disease (ADPKD).

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