Intra-individual variability of serum hepcidin-25 in haemodialysis patients using mass spectrometry and ELISA
Author(s) -
Hilde P.E. Peters,
Adam Rumjon,
Sukhvinder S. Bansal,
Coby M. Laarakkers,
Jan A.J.G. van den Brand,
Pantelis Sarafidis,
Rebecca Musto,
Jolanta Małyszko,
Dorine W. Swinkels,
Jack F.M. Wetzels,
Iain C. Macdougall
Publication year - 2012
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfs164
Subject(s) - hepcidin , medicine , dialysis , erythropoiesis , inflammation , hemodialysis , erythropoietin , quartile , serum iron , ceruloplasmin , endocrinology , gastroenterology , physiology , anemia , confidence interval
Measurement of serum hepcidin levels may provide a useful alternative to the current methods of determining iron status in chronic haemodialysis (HD) patients. However, the biological variability of this pivotal regulator of iron homeostasis is unclear, and the impact of inflammation, dialysis clearance and iron therapy on hepcidin variability has not been established.
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